One specific GNOME keyboard shortcut needs to be configured again regularly
I am a translator!
In GNOME on wayland, I have configured a keyboard shortcut for "show the run command prompt" as Super+P (because this is what I am used to from dwm). Regularly (but not always), when I open a session and I try this, no action. When I go to the settings, this is shown as set to Super+P. If I define it again to Super+P, it works again until the end of the session, and sometimes also for the next session.
I also have a "launch terminal" shortcut (Super+Shift+Enter of course), that one never had this problem. I also have Super+n and Super+Shift+n with n from 1 to 9 to switch or move the active window to a workspace (for this, I had to remove by gsettings some shortcuts not accessible via the GUI and make shortcuts with gsettings for workspaces 5 to 9 as it was not possible via the GUI), Super+Left/Right and Super+Shift+Left/Right to switch or move the active window to the workspace left/right, they also never had any problem.
So the problem is only with Super+P for "show the run command prompt" (which is what I almost always use to start apps). I don't know what could cause such a behaviour with this specific keyboard shortcut.
Leprechaun lore has it that Super+P may be bound to "switch-monitor" by default, wich may not have much visible effect if you are using a single monitor. You should be able to find that command in the keyboard shortcut settings, or in dconf, and remove the default Super+P keybind so you can use it for your favorite command instead.
If lore is correct, the dconf path should be something like /org/gnome/mutter/keybindings/switch-monitor. You can check it by running:
gsettings list-recursively | grep "<Super>p"